1031747-52-0Relevant academic research and scientific papers
Acid-promoted iron-catalysed dehydrogenative [4 + 2] cycloaddition for the synthesis of quinolines under air
Yang, Jinfei,Meng, Xiao,Lu, Kai,Lu, Zhihao,Huang, Minliang,Wang, Chengniu,Sun, Fei
, p. 31603 - 31607 (2018)
An acid-promoted iron-catalysed dehydrogenative [4 + 2] cycloaddition reaction was developed for the synthesis of quinolines using air as a terminal oxidant. Acetic acid was the best cocatalyst for the cycloaddition of N-alkyl anilines with alkenes or alk
Indium(III) trifluoromethanesulfonate: An efficient reusable catalyst for the alkynylation-cyclization of 2-aminoaryl ketones and synthesis of 2,4-disubstituted quinolines
Lekhok, Kushal C.,Prajapati, Dipak,Boruah, Ramesh C.
, p. 655 - 658 (2008)
An environmentally friendly and highly efficient procedure for the preparation of 2,4-disubstituted quinoline derivatives has been developed by a simple alkynylation-cyclization reaction of 2-aminoaryl ketones with phenylacetylenes in the presence of indi
Ionic liquid - An efficient recyclable system for the synthesis of 2,4-disubstituted quinolines via Meyer-Schuster rearrangement
Sarma, Rupam,Prajapati, Dipak
, p. 3001 - 3005 (2008)
An improved and eco-friendly method for the synthesis of 2,4-disubstituted quinolines via Meyer-Schuster rearrangement of 2-aminoaryl ketones and phenylacetylenes in the presence of zinc trifluoromethanesulfonate in [hmim]PF6 has been developed
Manganese(ii)-catalysed dehydrogenative annulation involving C-C bond formation: highly regioselective synthesis of quinolines
Wang, Chengniu,Yang, Jinfei,Meng, Xiao,Sun, Yufeng,Man, Xuyan,Li, Jinxia,Sun, Fei
supporting information, p. 4474 - 4478 (2019/04/05)
An inexpensive nontoxic manganese(ii)-catalysed dehydrogenative annulation was developed for C-C bond formation. The reaction showed high selectivity and efficiency across a broad substrate scope. Remarkably simple conditions and the ability to conduct gram-scale synthesis underscore this method's utility. To demonstrate the potential of this approach, we tested the drug effects of compound 3n, which showed activity for blocking vascular development. The results of this study will be important for the treatment of eye diseases and tumors caused by vascular proliferation.
Quinoline-containing skeleton compound and preparation method and applications thereof
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Paragraph 0037-0041, (2019/11/04)
The invention discloses a quinoline-containing skeleton compound and a preparation method thereof. A structural formula of the compound is represented by a formula I shown in the description. According to the invention, a series of quinoline derivatives are efficiently and rapidly synthesized by adopting cheap metal catalysis technology. The compound has a pharmaceutical effect on nervous system diseases and vascular system diseases, and broadens a treatment range of quinoline medicine.
Ligand promoted method for synthesizing polysubstituted quinoline under catalysis of cheap metal
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Paragraph 0060; 0061; 0062; 0063, (2018/12/05)
The invention discloses a ligand promoted method for synthesizing polysubstituted quinoline under the catalysis of cheap metal. According to the method disclosed by the invention, a substituted arylamine compound and a substituted olefin compound are used
