1031759-50-8Relevant articles and documents
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase
Hatano, Akihiko,Harano, Aiko,Takigawa, Yoshikatsu,Naramoto, Yasuhiro,Toda, Keisuke,Nakagomi, Yuuichi,Yamada, Hideyuki
, p. 3866 - 3870 (2008/12/20)
Thymidine phosphorylase (TP, EC 2.4.2.4) recognized the structure of the substrate with high specificity, via both the base and the ribosyl moieties. The replacement of 3′-OH of thymidine markedly influenced its catalytic activity with TP. The conversion