1031849-56-5

Basic information

• Product Name: 5-bromo-4-(trimethylsilyl)-2,3-dihydrofuro[2,3-b]pyridine
• CAS NO: 1031849-56-5
• Molecular Weight: 272.217
• Mol File: 1031849-56-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-bromo-4-(trimethylsilyl)-2,3-dihydrofuro[2,3-b]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-4-(trimethylsilyl)-2,3-dihydrofuro[2,3-b]pyridine(1031849-56-5)
• EPA Substance Registry System: 5-bromo-4-(trimethylsilyl)-2,3-dihydrofuro[2,3-b]pyridine(1031849-56-5)

Safety Data

• Hazardous Substances Data: 1031849-56-5(Hazardous Substances Data)

Upstream product

• 111097-47-3 2-(3-Butynyloxymethyl)pyrimidine 
• 1031849-54-3 2-{[4-(trimethylsilyl)but-3-yn-1-yl]oxy}pyrimidine 
• 1031849-55-4 4-(trimethylsilanyl)-2,3-dihydro-furo[2,3-b]pyridine 

Relevant articles and documents

Synthesis of 4-aza analog of ramelteon: A novel tricyclic 1,6,7,8-tetrahydro-2H-cyclopenta[d]furo[2,3-b]pyridine derivative as melatonin receptor ligand

The 4-aza analog of ramelteon (-)-1, a novel tricyclic 1,6,7,8-tetrahydro- 2H-cyclopenta[d]furo[2,3-b]pyridine derivative, was synthesized via the intramolecular inverse electron demand Diels-Alder reaction followed by fluoride-induced desilylation-cyclization.

TRICYCLIC COMPOUND AND MEDICAL USE THEREOF

The present invention provides a compound represented by the formula wherein R1 is a hydrocarbon group optionally having substituent(s), amino optionally having substituent(s), hydroxy optionally having a substituent or a heterocyclic group optionally having substituent(s), R2 is a hydrogen atom or a hydrocarbon group optionally having substituent(s), R3 is a hydrogen atom, a halogen atom, a hydrocarbon group optionally having substituent(s), amino optionally having substituent(s), hydroxy optionally having a substituent or mercapto optionally having a substituent, Xa to Xe are each a carbon atom or a nitrogen atom, m is 0 to 2, and ring A to ring C are each a ring optionally having substituent(s), or a salt thereof, which is useful as an agent for the prophylaxis or treatment of a disease relating to an action of melatonin, and the like.