1031883-61-0

Basic information

• Product Name: (R)-4-[(4-methoxybenzyl)oxy]piperidin-2-one
• Synonyms: (R)-4-[(4-methoxybenzyl)oxy]piperidin-2-one
• CAS NO: 1031883-61-0
• Molecular Weight: 235.283
• Mol File: 1031883-61-0.mol

Chemical Properties

• CAS DataBase Reference: (R)-4-[(4-methoxybenzyl)oxy]piperidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-[(4-methoxybenzyl)oxy]piperidin-2-one(1031883-61-0)
• EPA Substance Registry System: (R)-4-[(4-methoxybenzyl)oxy]piperidin-2-one(1031883-61-0)

Safety Data

• Hazardous Substances Data: 1031883-61-0(Hazardous Substances Data)

Upstream product

• 1031883-60-9 ethyl (R)-4-cyano-3-[(4-methoxybenzyl)oxy]butanoate 

Downstream Products

• 1031883-62-1 methyl (R)-4-[(4-methoxybenzyl)oxy]-2-oxopiperidine-1-carboxylate 

Relevant articles and documents

Stereoselective synthesis of (2S,4R)-4-hydroxypipecolic acid

A new synthetic route to enantiopure (2S,4R)-4-hydroxypipecolic acid from commercial ethyl (3S)-4-chloro-3-hydroxybutanoate is reported. The synthesis is based on the Pd-catalyzed methoxycarbonylation of a 4-alkoxy-substituted δ-valerolactam-derived vinyl triflate followed by the stereocontrolled hydrogenation of the enamine double bond. The final product was obtained after exhaustive hydrolysis in 20 % yield over 10 steps. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.