1031898-30-2Relevant academic research and scientific papers
Conjugated imines and iminium salts as versatile acceptors of nucleophiles
Shimizu, Makoto,Hachiya, Iwao,Mizota, Isao
scheme or table, p. 874 - 889 (2009/07/10)
Growing interests in nitrogen-containing molecules involving bioactive and functional materials have stimulated the recent development of synthetic methodologies where nucleophilic addition reactions to imino carbons are utilized in crucial steps. This article summarizes double nucleophilic addition reactions with α,β-unsaturated aldimines, addition reactions using alkynyl imines, "umpoled" reactions of α-imino esters, and the use of iminium salts as reactive electrophiles. The Royal Society of Chemistry 2009.
Synthesis of multi-substituted 2-iminopyridine by conjugate addition of ethyl cyanoacetate derivatives to alkynyl imines
Hachiya, Iwao,Minami, Yushi,Aramaki, Tetsuya,Shimizu, Makoto
experimental part, p. 1411 - 1417 (2009/04/06)
The synthesis of multi-substituted 2-iminopyridines by conjugate addition of ethyl cyanoacetate derivatives to alkynyl imines has been developed. The reaction of ethyl cyanoacetate derivatives with alkynyl imines provided multi-substituted 2-iminopyridine
