1031927-08-8 Usage
General Description
Methyl 4-(2-oxo-1,3-oxazinan-3-yl)benzoate, also known as moxaverine, is a chemical compound used in pharmaceuticals and medical research. It belongs to the class of 1,3-oxazinan-3-yl derivatives and is commonly employed as a smooth muscle relaxant and vasodilator. Moaxverine is believed to work by inhibiting the intracellular accumulation of calcium ions, leading to relaxation of smooth muscle and improved blood flow. Methyl 4-(2-oxo-1,3-oxazinan-3-yl)benzoate is used in the treatment of various gastrointestinal and circulatory disorders, such as irritable bowel syndrome, abdominal pain, and peripheral vascular disease. It also presents potential applications in the development of novel drugs for these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1031927-08-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,1,9,2 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1031927-08:
(9*1)+(8*0)+(7*3)+(6*1)+(5*9)+(4*2)+(3*7)+(2*0)+(1*8)=118
118 % 10 = 8
So 1031927-08-8 is a valid CAS Registry Number.
1031927-08-8Relevant articles and documents
SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa
Qiao, Jennifer X.,Chang, Chong-Hwan,Cheney, Daniel L.,Morin, Paul E.,Wang, Gren Z.,King, Sarah R.,Wang, Tammy C.,Rendina, Alan R.,Luettgen, Joseph M.,Knabb, Robert M.,Wexler, Ruth R.,Lam, Patrick Y.S.
, p. 4419 - 4427 (2008/02/10)
In the search of Factor Xa (FXa) inhibitors structurally different from the pyrazole-based series, we identified a viable series of enantiopure cis-(1R,2S)-cycloalkyldiamine derivatives as potent and selective inhibitors of FXa. Among them, cyclohexyldiam
