1031929-04-0

Basic information

• Product Name: (4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methanol
• Synonyms: (4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methanol
• CAS NO: 1031929-04-0
• Molecular Formula: C₁₃H₁₀F₃NO₂
• Molecular Weight: 269.2192096
• Product Categories: Hydroxymethyl's;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 1031929-04-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methanol(1031929-04-0)
• EPA Substance Registry System: (4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methanol(1031929-04-0)

Safety Data

• Hazardous Substances Data: 1031929-04-0(Hazardous Substances Data)

Usage

General Description

(4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methanol is a chemical compound with the molecular formula C14H11F3NO2. It is a white solid that is used in various chemical and pharmaceutical applications. The compound contains a phenyl ring with a hydroxyl group attached to it, as well as a pyridinyl group with a trifluoromethyl substituent. The presence of these functional groups makes it a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. (4-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methanol may have potential applications in the development of new drugs and other bioactive molecules due to its unique structure and properties. However, it is important to handle and use this compound with caution due to its potential health hazards and reactivity.

Upstream product

• 52334-81-3 2-chloro-5-trifluoromethylpyridine 
• 123-08-0 4-hydroxy-benzaldehyde 
• 103962-21-6 4-[{5-(trifluoromethyl)pyridin-2-yl}oxy]benzaldehyde 

Downstream Products

• 1160430-95-4 2-[4-(bromomethyl)phenoxy]-5-(trifluoromethyl)-pyridine 

Relevant articles and documents

Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 5-trifluoromethylpyridyl moiety

In this study, in order to find novel biologically active pyrazole oxime compounds, a series of pyrazole oxime derivatives containing a 5-trifluoromethylpyridyl moiety were synthesized. Preliminary bioassays indicated that most title compounds were found to display good to excellent acaricidal activity against Tetranychus cinnabarinus at a concentration of 200 μg/mL, and some designed compounds still showed excellent acaricidal activity against Tetranychus cinnabarinus at the concentration of 10 μg/mL, especially since the inhibition rates of compounds 8e, 8f, 8l, 8m, 8n, 8p, and 8q were all 100.00%. Interestingly, some target compounds exhibited moderate to good insecticidal activities against Plutella xylostella and Aphis craccivora at a concentration of 200 μg/mL; furthermore, compounds 8e and 8l possessed outstanding insecticidal activities against Plutella xylostella under the concentration of 50 μg/mL.

PYRIMIDINE DERIVATIVES AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE

Disclosed are compounds of formula (I) and or salts thereof which activate soluble guanylate cyclase (sGC), pharmaceutical compositions containing them, their use in the manufacture of a medicament for teating cardiovascular diseases, and processes for their preparation.