1032154-63-4Relevant academic research and scientific papers
Asymmetric ruthenium-catalyzed hydrogenation of 2- and 2,9-substituted 1,10-phenanthrolines
Wang, Tianli,Chen, Fei,Qin, Jie,He, Yan-Mei,Fan, Qing-Hua
supporting information, p. 7172 - 7176 (2013/07/26)
A 'Phen'atic: The title reaction proceeds in the presence of the chiral cationic ruthenium diamine catalyst (R,R)-1 (Tf=trifluoromethanesulfonyl, Ts=4-toluenesulfonyl). Both chiral 1,2,3,4-tetrahydro- and 1,2,3,4,7,8,9,10- octahydro-1,10- phenanthroline derivatives could be obtained in high yields with excellent enantio- and diastereoselectivity. Copyright
Br?nsted acid catalyzed asymmetric reduction of 2- and 2,9-substituted 1,10-phenanthrolines
Metallinos, Costa,Barrett, Fred B.,Xu, Shufen
, p. 720 - 724 (2008/12/22)
Several 2- and 2,9-substituted 1,10-phenanthrolines are reduced asymmetrically for the first time using a Hantzsch dihydropyridine in the presence of BINOL-derived phosphoric acid catalysts. The best results are obtained with phenanthrolines bearing unbranched or nitrogen-containing alkyl groups in the 2- or 2,9-positions, which afford chiral octahydrophenanthrolines in a range of yields (40-88%) and good to excellent levels of enantiomeric purity (78-99% ee). Georg Thieme Verlag Stuttgart.
