1032166-71-4Relevant academic research and scientific papers
3-Spirocyclopropanedihydro- and -tetrahydropyridin-4-ones from nitrone cycloadducts of bicyclopropylidene via 1-(1′-aminomethylcyclopropyl)- cyclopropanol under PdII catalysis
Revuelta, Julia,Cicchi, Stefano,De Meijere, Armin,Brandi, Alberto
experimental part, p. 1085 - 1091 (2009/04/05)
A series of 3-spirocyclopropanedihydro- and -tetrahydropyrid-4-ones have been synthesized by nitrone cycloaddition to 1,1′-bicyclopropylidene (BCP), chemoselective reduction of the N-O bond of the isoxazolidine ring, and PdII-catalyzed cascade rearrangement of the β-aminocyclopropanol derivatives into the final products. The new tetrahydropyridone derivatives were also prepared by thermal rearrangement of the isoxazolidines. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
