103224-64-2

Usage

Uses

Given the provided materials, there are no explicit uses listed for Ethanone, 1-[2,3,4,5-tetramethyl-6-(nitromethyl)phenyl]-. However, based on its chemical structure and the properties that may arise from its substituents, potential applications could include:
Used in Chemical Synthesis Industry:
Ethanone, 1-[2,3,4,5-tetramethyl-6-(nitromethyl)phenyl]could be used as an intermediate in the synthesis of various organic compounds, leveraging its unique structure and reactivity for the creation of pharmaceuticals, agrochemicals, or other specialty chemicals.
Used in Research and Development:
As a novel compound, Ethanone, 1-[2,3,4,5-tetramethyl-6-(nitromethyl)phenyl]may serve as a subject for research in organic chemistry to explore its properties, reactivity, and potential applications in new chemical reactions or processes.
Used in Material Science:
Ethanone, 1-[2,3,4,5-tetramethyl-6-(nitromethyl)phenyl]might be investigated for its potential use in the development of new materials, such as polymers or composites, where its specific structural features could impart unique characteristics to the material.

Upstream product

• 2040-01-9 2',3',4',5',6'-pentamethylacetophenone 
• 4124-31-6 trichloroacetic acid anhydride 
• 407-25-0 trifluoroacetic anhydride 

Relevant academic research and scientific papers

Positional Reactivity of Acylpolymethylbenzenes in Electrophilic Substitution

Friedel-Crafts acylation, bromination, deuteration, and nitration of acetylpentamethylbenzene (APMB), 1-acetyl-2,3,4,6-tetramethylbenzene (ATMB), and 1-benzoyl-2,3,4,6-tetramethylbenzene (BTMB) and the resulting product distribution were investigated.Friedel-Crafts acylation, bromination, and deuteration of APMB and Friedel-Crafts acylation of ATMB gave deacetylation-substitution products.On the other hand, bromination and deuteration of ATMB (or BTMB) and Friedel-Crafts acylation of BTMB gave 5-substituted products.In both cases, the positional reactivities were in accordance with the relative ?-complex stability.Conversely, except for Friedel-Crafts-type nitration, the positional reactivities in the nitration of these substrates were strikingly different from those of the above three reactions.Thus, side-chain functionalization at the 6-methyl group occurred in nitration with fuming nitric acid, depending on the solvents in use.The NMDO calculations and the reaction of APMB with single-electron transfer reagents such as tetranitromethane-hν or cerium(IV) ammonium nitrate suggest that the product distribution in nitration can be explained in terms of a single-electron transfer mechanism.

Regioselective Side-Chain Nitration of Polymethylbenzenes Directed by an Acyl Function and Its Application to the Synthesis of Polysubstituted Phthalic Acid Derivatives

Nitration of three types of tetramethylacetophenones and pentamethylacetophenone with fuming nitric acid in acetic anhydride was carried out.The product distributions were compared with those estimated from substituent effects.A variety of acylpentamethylbenzenes including pentamethylbenzoic acid were reacted with the nitrating system to give regioselectively 2-(nitromethyl)-3,4,5,6-tetramethylacylbenzenes.The selective nitrations of some benzoic acid derivatives followed by an alkaline treatment have been found to provide the N-hydroxyphthalimide derivatives, which a re readily converted to the phthalic anhydrides and the phthalazines.