1032290-70-2Relevant academic research and scientific papers
Sequential one-pot glycosidations catalytically promoted: Unprecedented strategy in oligosaccharide synthesis for the straightforward assemblage of the antitumor PI-88 pentasaccharide
Valerio, Silvia,Pastore, Antonello,Adinolfi, Matteo,Iadonisi, Alfonso
, p. 4496 - 4503 (2008/09/21)
(Chemical Equation Presented) The pentasaccharide sequence of the most active components of the antitumor drug PI-88, currently in phase II clinical trial, has been rapidly assembled in high overall yield and in only three steps starting from three monosa
Tunable activation of glycosyl trichloro- and (N-phenyl)trifluoro- acetimidates with ytterbium(III) triflate: One-pot synthesis of trisaccharides under catalytic conditions
Adinolfi, Matteo,Iadonisi, Alfonso,Ravidà, Alessandra
, p. 583 - 586 (2007/10/03)
A mild promoter such as Yb(OTf)3 allows selective activation of glycosyl trichloroacetimidate building blocks in the presence of glycosyl (N-phenyl)trifluoroacetimidates with a similar pattern of protecting groups. This selectivity has been exp
