1032349-93-1 Usage
Uses
A highly selective inhibitor of Akt. Akt1, IC50=8 nM; Akt2, IC50=12 nM; Akt3, IC50=65 nM.
Check Digit Verification of cas no
The CAS Registry Mumber 1032349-93-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,2,3,4 and 9 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1032349-93:
(9*1)+(8*0)+(7*3)+(6*2)+(5*3)+(4*4)+(3*9)+(2*9)+(1*3)=121
121 % 10 = 1
So 1032349-93-1 is a valid CAS Registry Number.
1032349-93-1Relevant articles and documents
Inhibitors of Akt activity
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Page/Page column 61, (2008/12/06)
The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.
