1032349-98-6 Usage
General Description
Tert-butyl 1-(4-(2-phenylacetyl)phenyl)cyclobutylcarbamate is a chemical compound with a molecular formula of C25H27NO3. It is a carbamate derivative and is classified as a tert-butyl carbamate. tert-butyl 1-(4-(2-phenylacetyl)phenyl)cyclobutylcarbaMate is commonly used in organic synthesis and pharmaceutical research. It has been studied for its potential therapeutic applications, particularly as a potential drug candidate for the treatment of various medical conditions. Tert-butyl 1-(4-(2-phenylacetyl)phenyl)cyclobutylcarbamate is known for its structural complexity and has attracted interest in the scientific community for its potential biological activities and pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1032349-98-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,2,3,4 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1032349-98:
(9*1)+(8*0)+(7*3)+(6*2)+(5*3)+(4*4)+(3*9)+(2*9)+(1*8)=126
126 % 10 = 6
So 1032349-98-6 is a valid CAS Registry Number.
1032349-98-6Relevant articles and documents
Diverse heterocyclic scaffolds as allosteric inhibitors of AKT
Kettle, Jason G.,Brown, Simon,Crafter, Claire,Davies, Barry R.,Dudley, Phillippa,Fairley, Gary,Faulder, Paul,Fillery, Shaun,Greenwood, Hannah,Hawkins, Janet,James, Michael,Johnson, Keith,Lane, Clare D.,Pass, Martin,Pink, Jennifer H.,Plant, Helen,Cosulich, Sabina C.
, p. 1261 - 1273 (2012/04/10)
Wide-ranging exploration of potential replacements for a quinoline-based inhibitor of activation of AKT kinase led to number of alternative, novel scaffolds with potentially improved potency and physicochemical properties. Examples showed predictable DMPK properties, and one such compound demonstrated pharmacodynamic knockdown of phosphorylation of AKT and downstream biomarkers in vivo and inhibition of tumor growth in a breast cancer xenograft model.
INHIBITORS OF AKT ACTIVITY
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, (2009/12/28)
The instant invention provides for substituted [1,2,4]triazolo[4,3-a]-1,5-naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms, preferably Akt1. The invention also pro