1032383-10-0Relevant articles and documents
Design and synthesis of trans 2-(furan-2-yl)vinyl heteroaromatic iodides with antitumour activity
Fortuna, Cosimo Gianluca,Barresi, Vincenza,Berellini, Giuliano,Musumarra, Giuseppe
, p. 4150 - 4159 (2008/09/21)
A new molecular modelling approach based on physico-chemical and pharmacokinetic properties, called Volsurf plus, was used to design new heterocyclic compounds with antiproliferative activity. The synthesis and in vitro antitumour tests on a breast carcinoma cell line (MCF7) confirmed VOLSURF predicted activity values.