103244-41-3

Basic information

• Product Name: IGF-II (33-40)
• Synonyms: INSULIN-LIKE GROWTH FACTOR II FRAGMENT 33-40;INSULIN-LIKE GROWTH FACTOR II (33-40);IGF-II (33-40);IGF-II C-PEPTIDE;H-SER-ARG-VAL-SER-ARG-ARG-SER-ARG-OH;SER-ARG-VAL-SER-ARG-ARG-SER-ARG
• CAS NO: 103244-41-3
• Molecular Formula: C38H74N20O12
• Molecular Weight: 1003.12
• Mol File: 103244-41-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: IGF-II (33-40)(CAS DataBase Reference)
• NIST Chemistry Reference: IGF-II (33-40)(103244-41-3)
• EPA Substance Registry System: IGF-II (33-40)(103244-41-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 103244-41-3(Hazardous Substances Data)

Usage

Description

IGF-II (33-40) is a peptide chemical compound derived from the insulin-like growth factor II (IGF-II) protein, which is crucial for cell growth and development. This specific fragment, indicated by the "33-40" designation, represents a sequence of amino acids within the larger protein. It has garnered research interest due to its potential role in enhancing cell proliferation and survival, with particular implications in the fields of cancer and neurodegenerative diseases. The fragment is thought to interact with various receptors and signaling pathways within the body, thereby exerting its biological influence. Ongoing studies aim to clarify the mechanisms by which IGF-II (33-40) operates and to explore its possible therapeutic uses.

Uses

Used in Pharmaceutical Research:
IGF-II (33-40) is utilized as a research compound for investigating its role in cell proliferation and survival. Its potential applications in the development of treatments for cancer and neurodegenerative diseases are of particular interest, as it may offer insights into disease mechanisms and the discovery of novel therapeutic targets.
Used in Cancer Therapy Development:
In the field of oncology, IGF-II (33-40) is used as a target for developing new cancer therapies. Its influence on cell proliferation and survival suggests that modulating its activity could have implications for treating cancer, particularly if it can be harnessed to inhibit tumor growth or enhance the effectiveness of existing treatments.
Used in Neurodegenerative Disease Research:
IGF-II (33-40) is also employed as a research tool in the study of neurodegenerative diseases. Given its role in cell survival, understanding how this peptide fragment interacts with neuronal cells could provide valuable information on the progression of such diseases and potentially lead to the development of neuroprotective therapies.
Used in Drug Discovery:
IGF-II (33-40) serves as a lead compound in drug discovery efforts. Its interaction with specific receptors and signaling pathways makes it a promising candidate for the design of new drugs that could target these pathways to treat a variety of conditions, including cancer and neurodegenerative diseases.