1032528-06-5

Basic information

• Product Name: tert-butyl 1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutylcarbaMate
• Synonyms: tert-butyl 1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutylcarbaMate;[1-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)phenyl]cyclobutyl]carbamic acid tert-butyl ester;CarbaMic acid, N-[1-[4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutyl]-, 1,1-diMethylethyl ester;N-[1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutyl]Carbamic acid 1,1-dimethylethyl ester;tert-Butyl (1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)
• CAS NO: 1032528-06-5
• Molecular Formula: C₂₁H₃₂BNO₄
• Molecular Weight: 373.29408
• Mol File: 1032528-06-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 481.0±34.0 °C(Predicted)
• Appearance: /
• Density: 1.08
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 11.98±0.20(Predicted)
• CAS DataBase Reference: tert-butyl 1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutylcarbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutylcarbaMate(1032528-06-5)
• EPA Substance Registry System: tert-butyl 1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutylcarbaMate(1032528-06-5)

Safety Data

• Hazardous Substances Data: 1032528-06-5(Hazardous Substances Data)

Usage

General Description

Tert-butyl 1-(4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclobutylcarbaMate is a complex organic compound with a molecular formula of C20H29BO4N. It is composed of a tert-butyl carbamate group attached to a cyclobutyl ring, which is further connected to a phenyl ring substituted with a 4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl group. This chemical is commonly used in chemical research and pharmaceutical development due to its unique structural properties and potential applications in drug synthesis and medicinal chemistry.

Upstream product

• 485828-58-8 1-(4- bromophenyl)cyclobutane-1-carbonitrile 
• 16532-79-9 4-Bromophenylacetonitrile 
• 1032350-06-3 tert-butyl (1-(4-bromophenyl)cyclobutyl)carbamate 
• 73183-34-3 bis(pinacol)diborane 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1032349-96-4 tert-butyl [1-(4-chlorophenyl)cyclobutyl]carbamate 
• 1094218-30-0 1-(4-bromophenyl)cyclobutanamine 
• 1193389-40-0 1-(4-bromophenyl)cyclobutane-1-amine hydrochloride 

Downstream Products

• 1032528-04-3 tert-butyl {1-[4-(2-phenyl-9-pyrazin-2-yl[1,2,4]triazolo[4',3':1,6]pyrido[2,3-b]pyrazin-3-yl)phenyl]cyclobutyl}carbamate 
• 1301611-58-4 tert-butyl 1-(4-(3-methyl-4-oxo-5-phenyl-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutylcarbamate 
• 1301609-40-4 6-(4-(1-aminocyclobutyl)phenyl)-3-methyl-5-phenylfuro[2,3-d]pyrimidin-4(3H)-one 
• 1301612-24-7 tert-butyl 1-(4-(3-(cyclopropylmethyl)-4-oxo-5-phenyl-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutylcarbamate 
• 1301612-26-9 tert-butyl 1-(4-(3-(2-hydroxyethyl)-4-oxo-5-phenyl-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutylcarbamate 
• 1301612-28-1 tert-butyl 1-(4-(3-(2-fluoroethyl)-4-oxo-5-phenyl-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutylcarbamate 
• 1301612-29-2 tert-butyl 1-(4-(3-ethyl-4-oxo-5-phenyl-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutylcarbamate 
• 1301612-31-6 tert-butyl 1-(4-(3-(2-methoxyethyl)-4-oxo-5-phenyl-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutylcarbamate 
• 1301612-33-8 tert-butyl 1-(4-(4-oxo-5-phenyl-3-(2,2,2-trifluoroethyl)-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutylcarbamate 
• 1301612-35-0 tert-butyl 1-(4-(3-isopropyl-4-oxo-5-phenyl-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutylcarbamate 
• 1301612-37-2 tert-butyl (1-(4-(3-(2,2-difluoroethyl)-4-oxo-5-phenyl-3,4-dihydrofuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutyl)carbamate 
• 1301609-82-4 6-(4-(1-aminocyclobutyl)phenyl)-3-(2,2-difluoroethyl)-5-phenylfuro[2,3-d]pyrimidin-4(3H)-one 
• 1301608-86-5 6-(4-(1-aminocyclobutyl)phenyl)-5-phenylfuro[2,3-d]pyrimidin-4(3H)-one 
• 1301610-83-2 tert-butyl (1-(4-(5-phenylfuro[2,3-d]pyrimidin-6-yl)phenyl)cyclobutyl)carbamate 

Relevant articles and documents

PHARMACEUTICALLY ACTIVE COMPOUNDS

The invention is directed to compounds of general formula (I), and pharmaceutical compositions containing such compounds. The compounds and compositions have valuable pharmaceutical properties. In particular, they may be used for the treatment of cancer. Novel intermediates and novel methods of preparation are also disclosed.

NOVEL IMIDAZO-OXAZINE COMPOUND OR SALT THEREOF

The present invention provides an imidazooxazine compound represented by Formula (I) or a salt thereof, wherein A, B, C, and D are as defined in the specification.

BICYCLIC PYRIMIDINES

Compounds of formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.