1032602-56-4Relevant academic research and scientific papers
Direct and waste-free amidations and cycloadditions by organocatalytic activation of carboxylic acids at room temperature
Al-Zoubi, Raed M.,Marion, Olivier,Hall, Dennis G.
, p. 2876 - 2879 (2008)
(Chemical Equation Presented) Taming carboxylic acids: ortho-Iodo- and ortho-bromophenylboronic acids are exceptional organocatalysts in atom-economical amidations between free carboxylic acids and amines, including functionalized ones, and can also provide LUMO-lowering activation in [4 + 2] cycloadditions of α,β-unsaturated carboxylic acids.
Tuning catalysis of boronic acids in microgels by: In situ reversible structural variations
Zhai, Zhenghao,Du, Xue,Wu, Qingshi,Zhu, Lin,Farooqi, Zahoor H.,Li, Jin,Lan, Ruyue,Wang, Yusong,Wu, Weitai
, p. 3734 - 3744 (2020/02/04)
The catalysis of boronic acids immobilized in polymer microgels can be modulated by bubbling with N2/CO2 gas, and in some cases by adding glucose, making their catalytic activity comparable or even superior to that of the corresponding free boronic acid monomers homogeneously dispersed in solutions and, more importantly, making these boronic-acid-containing polymer microgels able to catalyze alternate reactions that may extend the usefulness. This enhanced catalytic function of these boronic-acid-containing microgels as organoboron acid catalysts is plausibly achieved via in situ reversibly structural variations. Kinetic studies have been carried out on the model boronic-acid-catalyzed aza-Michael addition, aldol, amidation, and [4 + 2] cycloaddition reactions in order to better understand the catalytic process.
