1032650-41-1

Basic information

• Product Name: 7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine
• Synonyms: 7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine;7-broMo-4-chloro-5H-pyrrolo[3;7-BroMo-4-chloro-5H-pyrro...;5H-Pyrrolo[3,2-d]pyriMidine,7-broMo-4-chloro-
• CAS NO: 1032650-41-1
• Molecular Formula: C₆H₃BrClN₃
• Molecular Weight: 232.46512
• Product Categories: CHIRAL CHEMICALS;pyrimidine;Heterocycle-Pyrimidine series
• Mol File: 1032650-41-1.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 384.3±37.0 °C(Predicted)
• Appearance: /
• Density: 1.996±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 9.91±0.40(Predicted)
• CAS DataBase Reference: 7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine(1032650-41-1)
• EPA Substance Registry System: 7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine(1032650-41-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 1032650-41-1(Hazardous Substances Data)

Usage

General Description

7-bromo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine is a chemical compound with the molecular formula C6H3BrClN3. It is a heterocyclic compound that contains both a pyrrolo and pyrimidine ring. This chemical is used in the field of pharmaceutical research as a building block for the synthesis of various biologically active compounds, particularly in the development of potential anticancer and antiviral drugs. It has also been studied for its potential application in the field of materials science, particularly in the development of organic semiconductors and organic electronic devices. The compound exhibits properties that make it suitable for use in organic synthesis and has the potential for further exploration in various fields of research.

Upstream product

• 93587-23-6 7-bromo-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one 
• 84905-80-6 4-Chloro-5H-pyrrolo[3,2-d]pyrimidine 

Downstream Products

• 1032648-89-7 1-(4-chloro-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-2,2,2-trifluoro-1-[1-(4-fluorophenyl)-1H-indazol-5-yl]ethanol 
• 1384950-69-9 5-methyl-7-(4-methanesulfonylphenyl)-4-(piperidin-4-yloxy)-5H-pyrrolo[3,2-d]pyrimidine 
• 1384950-68-8 tert-butyl 4-(5-methyl-7-(4-methanesulfonylphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)piperidin-1-carboxylate 
• 1334712-78-5 5-(4-chlorophenyl)-7-(oxan-4-yl)-5H-pyrrolo[3,2-d]pyrimidine 

Relevant articles and documents

AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY

Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.

NOVEL PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION INCLUDING SAME AS AN ACTIVE INGREDIENT

The present invention relates to a compound represented by formula (I) for inhibiting the activity of diacylglycerol O-acyltransferase type 1 (DGAT1), and pharmaceutically acceptable salts thereof, and a pharmaceutical composition comprising same as an active ingredient. The compound of the present invention may be used effectively in the treatment or prevention of a disease or condition mediated by the activity of DGAT1 such as obesity, type II diabetes, dyslipidemia, metabolic syndrome, and the like, without any adverse effects: wherein A, B, X, and R5 to R7 are the same as defined in the specification.

NEW BICYCLIC COMPOUND FOR MODULATING G PROTEIN-COUPLED RECEPTORS

The present invention relates to a bicyclic compound for modulating G protein-coupled receptors. The inventive compound provides preventing or treating a disease associated with the modulation of G protein-coupled receptors, particularly GPR119 G protein-coupled receptors.