1032661-64-5

Basic information

• Product Name: 8-O-ethyl-9,10-di-O-benzoyl-5,7-dioxa-3-thia-2-azabicyclo[3.3.1]decane-3,3-dioxide
• Synonyms: 8-O-ethyl-9,10-di-O-benzoyl-5,7-dioxa-3-thia-2-azabicyclo[3.3.1]decane-3,3-dioxide
• CAS NO: 1032661-64-5
• Molecular Weight: 477.492
• Mol File: 1032661-64-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-O-ethyl-9,10-di-O-benzoyl-5,7-dioxa-3-thia-2-azabicyclo[3.3.1]decane-3,3-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 8-O-ethyl-9,10-di-O-benzoyl-5,7-dioxa-3-thia-2-azabicyclo[3.3.1]decane-3,3-dioxide(1032661-64-5)
• EPA Substance Registry System: 8-O-ethyl-9,10-di-O-benzoyl-5,7-dioxa-3-thia-2-azabicyclo[3.3.1]decane-3,3-dioxide(1032661-64-5)

Safety Data

• Hazardous Substances Data: 1032661-64-5(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 1032661-43-0 (2R,3S,4R)-3-sulfamoyloxymethyl-3,4-dihydro-2H-pyran-2-benzoyloxymethyl-4-yl-benzoate 

Relevant articles and documents

Stereocontrolled intramolecular aziridination of glycate: Ready access to aminoglycosides and mechanistic insights from DFT studies

Stereocontrolled intramolecular aziridination of the glycal-derived sulfamates offers a highly efficient strategy to divergently prepare aminoglycosides. Rhodium-catalyzed nitrogen-atom transfer to C=C bonds formed semistable aziridines, which were subjected to various nucleophiles (C, O, S, and N) to give cyclic sulfamate-containing aminosugar derivatives selectively. The second nucleophilic displacement of sulfonyloxy moieties of [1,2,3]-oxathiazepane-2,2-dioxides allows straightforward access to aminoglycosides with selective α- or β-linkages. This approach is operationally simple, complements existing methods, and is a versatile protocol for the synthesis of polyfunctionalized amino sugars. In addition, the mechanism of the rhodium-catalyzed intramolecular aziridination of glycals and its ring-opening reaction was extensively studied by using DFT calculations.