1032815-07-8

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 4-chloro-1-(phenylsulfonyl)-
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 4-chloro-1-(phenylsulfonyl)-;4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde;1-(benzenesulfonyl)-4-chloropyrrolo[2,3-b]pyridine-5-carbaldehyde
• CAS NO: 1032815-07-8
• Molecular Formula: C₁₄H₉ClN₂O₃S
• Molecular Weight: 320.75086
• Mol File: 1032815-07-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 4-chloro-1-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 4-chloro-1-(phenylsulfonyl)-(1032815-07-8)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 4-chloro-1-(phenylsulfonyl)-(1032815-07-8)

Safety Data

• Hazardous Substances Data: 1032815-07-8(Hazardous Substances Data)

Usage

Structure

Pyrrolopyridine derivative with a chloro-substituted phenylsulfonyl group attached to the 4-position on the pyrrolopyridine ring

Potential applications

Medicinal chemistry (pharmaceuticals and agrochemicals development), drug discovery and development research

Unique structure

Valuable building block for the synthesis of various organic compounds

Functional groups

Chloro, phenylsulfonyl, pyrrolopyridine, carboxaldehyde

Interaction with biological targets

Of interest for research in drug discovery and development

Upstream product

• 651744-48-8 4-chloro-1-triisopropylsilanyl-1H-pyrrolo[2,3-b]pyridine 
• 55052-28-3 4-chloro-7-azaindole 
• 55052-24-9 1H-Pyrrolo[2,3-b]pyridine-7-oxide 
• 271-63-6 7-Azaindole 
• 958230-19-8 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 1032815-08-9 4-chloro-5-(1,3-dioxolan-2-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine 
• 1513857-77-6 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholin-4-ylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3’,2’:5,6]pyrido[4,3-d]pyrimidin-2-one 

Relevant articles and documents

DERIVATIVES OF AN FGFR INHIBITOR

The present disclosure relates to derivatives (e.g., hydroxyl, keto, glucuronide, sulfonic acid, and deuterated) of a Fibroblast Growth Factor Receptors (FGFR) inhibitor, including methods of preparation thereof, and intermediates in the preparation thereof, which are useful in the treatment of FGFR mediated disease such as cancer.

SUBSTITUTED TRICYCLIC COMPOUNDS AS FGFR INHIBITORS

The present invention relates to tricyclic compounds, and pharmaceutical compositions of the same, that are inhibitors of one or more FGFR enzymes and are useful in the treatment of FGFR-associated diseases such as cancer.