1032818-12-4Relevant articles and documents
Diethylammonium iodide as catalyst for the metal-free synthesis of 5-aryl-2-oxazolidinones from aziridines and carbon dioxide
Bresciani, Giulio,Bortoluzzi, Marco,Pampaloni, Guido,Marchetti, Fabio
, p. 4152 - 4161 (2021/05/19)
The catalytic potential of ammonium halide salts was explored in the coupling reaction of a model aziridine with carbon dioxide, highlighting the superior activity of [NH2Et2]I. Then, working at room temperature, atmospheric CO2 pressure and in the absenc
Diastereoselective Construction of Cyclopropane-Fused Tetrahydroquinolines via a Sequential [4 + 2]/[2 + 1] Annulation Reaction
Wang, Zhen-Hua,Shen, Li-Wen,Xie, Ke-Xin,You, Yong,Zhao, Jian-Qiang,Yuan, Wei-Cheng
supporting information, p. 3114 - 3118 (2020/04/20)
A sequential [4 + 2]/[2 + 1] annulation of α-aryl vinylsulfoniums with 2-aminochalcones and 2-(2-aminobenzylidene)-1H-indene-1,3(2H)-dione is reported that affords a series of cyclopropane-fused tetrahydroquinolines. The salient features of this novel and practical transformation include high efficiency, transition-metal-free nature, operational simplicity, and outstanding functional group tolerance.
A facile and regioselective multicomponent synthesis of chiral aryl-1,2-mercaptoamines in water followed by monoamine oxidase (MAO-N) enzymatic resolution
Lauder, Kate,Masci, Domiziana,Toscani, Anita,Al Mekdad, Aya,Black, Gary W.,Brown, Nicola L.,Turner, Nicholas J.,Luisi, Renzo,Castagnolo, Daniele
supporting information, p. 8982 - 8986 (2019/10/28)
A facile microwave assisted three-component protocol allows the synthesis of chiral aryl-1,2-mercaptoamines in water in a few minutes with high yields, bypassing the use of toxic aziridine intermediates. The chiral 1,2-mercaptoamines were then deracemized through enzymatic resolution of the racemates using monoamine oxidase (MAO-N) biocatalysts.
