1032827-77-2

Basic information

• Product Name: 2-((R)-3-(4-bromo-3-fluorophenylamino)-2-hydroxypropyl)isoindolin-1,3-dione
• Synonyms: 2-((R)-3-(4-bromo-3-fluorophenylamino)-2-hydroxypropyl)isoindolin-1,3-dione
• CAS NO: 1032827-77-2
• Molecular Weight: 393.212
• Mol File: 1032827-77-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((R)-3-(4-bromo-3-fluorophenylamino)-2-hydroxypropyl)isoindolin-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((R)-3-(4-bromo-3-fluorophenylamino)-2-hydroxypropyl)isoindolin-1,3-dione(1032827-77-2)
• EPA Substance Registry System: 2-((R)-3-(4-bromo-3-fluorophenylamino)-2-hydroxypropyl)isoindolin-1,3-dione(1032827-77-2)

Safety Data

• Hazardous Substances Data: 1032827-77-2(Hazardous Substances Data)

Upstream product

• 656-65-5 3-fluoro-4-bromophenylamine 
• 161596-47-0 (S)-N-glycidylphthalimide 

Downstream Products

• 1032827-78-3 (S)-2-((3-(4-bromo-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)isoindoline-1,3-dione 
• 856677-03-7 (S)-5-(aminomethyl)-3-(4-bromo-3-fluorophenyl)oxazolidin-2-one 
• 1032827-88-5 (S)-N-((3-(4-(4-(1,4,5,6-tetrahydro-pyrimidin-2-yl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032897-88-3 (S,Z)-N-((3-(4-(4-(N'-hydroxycarbamimidoyl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032827-87-4 (S)-N-((3-(4-(4-(4,5-dihydro-1H-imidazol-2-yl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032827-83-0 (S)-N-((3-(4-(4-(4,5-dihydro-5,5-dimethyl-1,2,4-oxadiazol-3-yl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032827-86-3 (S,Z)-N-((3-(4-(4-(4,5-dihydro-1-methyl-1H-imidazol-2-yl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032827-84-1 (S)-N-((3-(4-(4-(5-oxo-1,2,4-oxadiazol-3-yl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032827-81-8 (S)-N-((3-(4-(4-(N-hydroxycarbamoyl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032897-90-7 (S,Z)-N-((3-(4-(4-(N'-methoxycarbamimidoyl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032827-80-7 (S,E)-methyl 3-(4-(2-fluoro-4-(5-(acetamidomethyl)-2-oxooxazolidin-3-yl)phenyl)phenyl)acrylate 
• 1032827-82-9 (S)-N-((3-(4-(4-(carbamimidoyl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032827-76-1 N-(((S)-3-(4-(4-ethoxycarbonylphenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 
• 1032827-79-4 (S,E)-N-((3-(4-(4-(2-nitrovinyl)phenyl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide 

Relevant articles and documents

NOVEL OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

The present invention relates to a novel oxazolidinone derivative, its prodrugs, hydrates, solvates, isomers, pharmaceutically permitted salts, and its preparation methods and pharmaceutical compositions containing the same. The oxazolidinone derivative and its pharmaceutically permitted salts according to the present invention have wide antimicrobial spectrum against resistant bacteria and low toxicity, and they show strong antibacterial effect against gram-positive and gram-negative pathogens. So, they can be used as good antibiotics.