103302-12-1

Basic information

• Product Name: EPILACTOSE
• Synonyms: 4-O-(b-D-Galactopyranosyl)-a-D-mannopyranosemonohydrate;3-O-beta-D-Galactopyranosyl-alpha-D-mannopyranose
• CAS NO: 103302-12-1
• Molecular Formula: C₁₂H₂₂O₁₁
• Molecular Weight: 0
• Mol File: 103302-12-1.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: EPILACTOSE(CAS DataBase Reference)
• NIST Chemistry Reference: EPILACTOSE(103302-12-1)
• EPA Substance Registry System: EPILACTOSE(103302-12-1)

Safety Data

• Hazardous Substances Data: 103302-12-1(Hazardous Substances Data)

Upstream product

• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 
• 74808-09-6 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl trichloroacetimidate 
• 64801-10-1 2,3,4,6-tetra-O-benzyl-1-O-(N-methylacetimidoyl)-β-D-galactopyranose 
• 61236-87-1 allyl 2,4,6-tri-O-benzyl-α-D-galactopyranoside 
• 56341-65-2 Benzyl 4,6-O-benzylidene-β-D-galactopyranoside 
• 10257-28-0 D-Galactose 
• 2816-24-2 o-nitrophenyl D-galactopyranoside 
• 2280-44-6 D-Glucose 
• 76939-53-2 α-D-glucosyl-1-phosphate 
• 66432-48-2 benzyl 2-O-benzoyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 76819-25-5 benzyl 2-O-benzoyl-4,6-O-benzylidene-3-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 76819-18-6 2-O-acetyl-4,6-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 76819-21-1 benzyl 4,6-O-benzylidene-3-O-α-D-glucopyranosyl-α-D-glucopyranoside 

Downstream Products

• 50-99-7 D-glucose 
• 91463-79-5 2-O-β-D-glucopyranosyl-D-xylose 
• 5077-26-9 3-O-β-D-glucopyranosyl-D-xylose 
• 97-30-3 methyl D-galactopyranoside 
• 51157-42-7 octo-O-acetyllaminaribose 
• 499-16-1 O-β-D-galactopyranosyl-(1->3)-D-galactitol 
• 59-23-4 D-Galactose 
• 534-68-9 2-O-β-D-glucosyl-glycerol 
• 158110-30-6 (2R)-1-O-acetyl-2-O-(β-D-glucopyranosyl)glycerol 
• 131749-72-9 3-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-β-D-glucopyranosyl)-D-glyceraldehyde 1,1-diethyl acetal 
• 131749-75-2 3-O-acetyl-1-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-β-D-glucopyranosyl)-sn-glycerol 
• 131749-74-1 1-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-β-D-glucopyranosyl)-sn-glycerol 
• 131749-73-0 3-O-benzyl-2-O-(2',3',4',6'-tetra-O-benzyl-β-D-glucopyranosyl)-D-glyceraldehyde 

Relevant articles and documents

Orthogonal Active-Site Labels for Mixed-Linkage endo-β-Glucanases

Small molecule irreversible inhibitors are valuable tools for determining catalytically important active-site residues and revealing key details of the specificity, structure, and function of glycoside hydrolases (GHs). β-glucans that contain backbone β(1,3) linkages are widespread in nature, e.g., mixed-linkage β(1,3)/β(1,4)-glucans in the cell walls of higher plants and β(1,3)glucans in yeasts and algae. Commensurate with this ubiquity, a large diversity of mixed-linkage endoglucanases (MLGases, EC 3.2.1.73) and endo-β(1,3)-glucanases (laminarinases, EC 3.2.1.39 and EC 3.2.1.6) have evolved to specifically hydrolyze these polysaccharides, respectively, in environmental niches including the human gut. To facilitate biochemical and structural analysis of these GHs, with a focus on MLGases, we present here the facile chemo-enzymatic synthesis of a library of active-site-directed enzyme inhibitors based on mixed-linkage oligosaccharide scaffolds and N-bromoacetylglycosylamine or 2-fluoro-2-deoxyglycoside warheads. The effectiveness and irreversibility of these inhibitors were tested with exemplar MLGases and an endo-β(1,3)-glucanase. Notably, determination of inhibitor-bound crystal structures of a human-gut microbial MLGase from Glycoside Hydrolase Family 16 revealed.

Characterization of a laminaribiose phosphorylase from Acholeplasma laidlawii PG-8A and production of 1,3-β-d-glucosyl disaccharides

We identified a glycoside hydrolase family 94 homolog (ACL0729) from Acholeplasma laidlawii PG-8A as a laminaribiose (1,3-β-d-glucobiose) phosphorylase (EC 2.4.1.31). The recombinant ACL0729 produced in Escherichia coli catalyzed phosphorolysis of laminar

Mode of operation and low-resolution structure of a multi-domain and hyperthermophilic endo-β-1,3-glucanase from Thermotoga petrophila

1,3-β-Glucan depolymerizing enzymes have considerable biotechnological applications including biofuel production, feedstock-chemicals and pharmaceuticals. Here we describe a comprehensive functional characterization and low-resolution structure of a hyperthermophilic laminarinase from Thermotoga petrophila (TpLam). We determine TpLam enzymatic mode of operation, which specifically cleaves internal β-1,3-glucosidic bonds. The enzyme most frequently attacks the bond between the 3rd and 4th residue from the non-reducing end, producing glucose, laminaribiose and laminaritriose as major products. Far-UV circular dichroism demonstrates that TpLam is formed mainly by beta structural elements, and the secondary structure is maintained after incubation at 90. °C. The structure resolved by small angle X-ray scattering, reveals a multi-domain structural architecture of a V-shape envelope with a catalytic domain flanked by two carbohydrate-binding modules.