1033039-28-9

Basic information

• Product Name: C₅₅H₈₇N₅O₁₃
• Synonyms: C₅₅H₈₇N₅O₁₃
• CAS NO: 1033039-28-9
• Molecular Weight: 1026.32
• Mol File: 1033039-28-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₅H₈₇N₅O₁₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₅H₈₇N₅O₁₃(1033039-28-9)
• EPA Substance Registry System: C₅₅H₈₇N₅O₁₃(1033039-28-9)

Safety Data

• Hazardous Substances Data: 1033039-28-9(Hazardous Substances Data)

Upstream product

• 880644-84-8 N-[(R)-2-amino-3-(p-aminophenyl)propyl]-trans-(S,S)-cyclohexane-1,2-diamine-N,N,N',N'',N''-penta-tert-butyl acetate 
• 55750-53-3 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid 

Downstream Products

• 1033039-29-0 C₃₅H₄₇N₅O₁₃ 

Relevant articles and documents

A novel bifunctional maleimido CHX-A″ chelator for conjugation to thiol-containing biomolecules

A novel bifunctional maleimido CHX-A″ DTPA chelator 5 was developed and conjugated to the monoclonal antibody trastuzumab (Herceptin) and subsequently radiolabeled with 111In. The resulting 111In labeled immunoconjugate 2 was demonstrated to bind to SKOV-3 ovarian cancer cells comparably to an isothiocyanato CHX-A″ DTPA modified native trastuzumab, 1. Through efficient thiol-maleimide chemistry, antibodies, peptides or other targeting vectors can now be modified with an established radioactive metal chelating agent CHX-A″ DTPA for imaging and/or therapies of cancer.