1033052-69-5Relevant academic research and scientific papers
First example of s-BuLi/(-)-sparteine-mediated chiral deprotonation of a piperazine and proof of the sense of induction
McDermott, Benjamin P.,Campbell, Andrew D.,Ertan, Anne
, p. 875 - 879 (2008)
This paper describes the first known example of a (-)-sparteine-mediated asymmetric deprotonation of a piperazine. Reaction of tert-butyl 4-tert-butylpiperazine-l-carboxylate with s-BuLi in the presence of (-)-sparteine at -78°C and quenching with carbon
