1033129-99-5Relevant academic research and scientific papers
Asymmetric synthesis of vicinal amino alcohols: Xestoaminol C, sphinganine and sphingosine
Abraham, Elin,Davies, Stephen G.,Millican, Nicholas L.,Nicholson, Rebecca L.,Roberts, Paul M.,Smith, Andrew D.
supporting information; experimental part, p. 1655 - 1664 (2008/10/09)
The highly diastereoselective anti-aminohydroxylation of α,β-unsaturated esters, via conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl)amide and subsequent in situ enolate oxidation with (+)-(camphorsulfonyl)oxaziridine, has been used as the key step in the asymmetric synthesis of N,O-diacetyl xestoaminol C (41% yield over 8 steps), N,O,O-triacetyl sphinganine (30% yield over 8 steps) and N,O,O-triacetyl sphingosine (30% yield over 7 steps). The Royal Society of Chemistry 2008.
Asymmetric synthesis of N,O,O,O-tetra-acetyl d-lyxo-phytosphingosine, jaspine B (pachastrissamine), 2-epi-jaspine B, and deoxoprosophylline via lithium amide conjugate addition
Abraham, Elin,Brock, E. Anne,Candela-Lena, José I.,Davies, Stephen G.,Georgiou, Matthew,Nicholson, Rebecca L.,Perkins, James H.,Roberts, Paul M.,Russell, Angela J.,Sánchez-Fernández, Elena M.,Scott, Philip M.,Smith, Andrew D.,Thomson, James E.
scheme or table, p. 1665 - 1673 (2008/10/09)
The highly diastereoselective anti-aminohydroxylation of (E)-γ-tri-iso-propylsilyloxy-α,β-unsaturated esters, via conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl)amide and subsequent in situ enolate oxidation with (+)-(camphorsulfonyl)oxaziri
