103322-59-4Relevant academic research and scientific papers
Design and Synthesis of Potent, Selective, and Orally Active Fluorine-Containing Renin Inhibitors
Doherty, Annette M.,Sircar, Ila,Kornberg, Brian E.,Quin, John,Winters, Thomas R.,et al.
, p. 2 - 14 (2007/10/02)
A series of primate renin inhibitors containing difluorocarbinol and difluoroketone groups at the P1 - P1' position have been synthesized and studied both in vitro and in vivo.In vitro, the compounds were evaluated as inhibitors of m
