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2,5-diaminothiazolo(5,4-d)pyrimidin-7(6H)-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

103322-70-9

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103322-70-9 Usage

Class

Heterocyclic compound

Structure

Contains a thiazole and pyrimidine ring system

Use

Synthetic intermediate in the preparation of pharmaceutical compounds

Pharmacological Activities

Potential as an antiviral and anticancer agent, studied for treating neurodegenerative disorders

Importance

Versatile and valuable compound for medicinal chemistry research and drug development

Check Digit Verification of cas no

The CAS Registry Mumber 103322-70-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,3,2 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 103322-70:
(8*1)+(7*0)+(6*3)+(5*3)+(4*2)+(3*2)+(2*7)+(1*0)=69
69 % 10 = 9
So 103322-70-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H5N5OS/c6-4-9-2(11)1-3(10-4)12-5(7)8-1/h(H2,7,8)(H3,6,9,10,11)

103322-70-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,5-diamino-6H-[1,3]thiazolo[5,4-d]pyrimidin-7-one

1.2 Other means of identification

Product number -
Other names Dat-5P

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103322-70-9 SDS

103322-70-9Upstream product

103322-70-9Downstream Products

103322-70-9Relevant academic research and scientific papers

Inhibitors of Human Purine Nucleoside Phosphorylase. Synthesis, Purine Nucleoside Phosphorylase Inhibition, and T-Cell Cytotoxicity of 2,5-Diaminothiazolopyrimidin-7(6H)-one and 2,5-Diaminothiazolopyrimidin-7-(6H)-one. Two Thio Isosteres of 8-Aminoguanine.

Sircar, Jagadish C.,Suto, Mark J.,Scott, Mary E.,Dong, Mi K.,Gilbertsen, Richard B.

, p. 1804 - 1806 (1986)

8-Aminoguanine is a potent inhibitor of purine nucleoside phosphorylase (PNP) and also a substrate of PNP.Two thioisosteres of 8-aminoguanine, 2,5-diaminothiazolopyrimidin-7(6H)-one (2) and 2,4-diaminothiazolopyrimidin-7(6H)-one (3), which cannot be substrates of PNP, were synthesized and evaluated for their inhibitory activity against PNP.They were found to be weak inhibitors of PNP and to be noncytotoxic for MOLT-4 T-cells in culture.

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