1033225-43-2

Basic information

• Product Name: 2,6-DIFLUORO-N-(2-NITROPHENYL)BENZENAMINE
• Synonyms: 2,6-DIFLUORO-N-(2-NITROPHENYL)BENZENAMINE;2,6-Difluoro-N-(2-nitrophenyl)aniline
• CAS NO: 1033225-43-2
• Molecular Formula: C₁₂H₈F₂N₂O₂
• Molecular Weight: 250
• Product Categories: Fluorine series
• Mol File: 1033225-43-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 296℃
• Flash Point: 133℃
• Appearance: Kind of white to yellow powder
• Density: 1.423
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,6-DIFLUORO-N-(2-NITROPHENYL)BENZENAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DIFLUORO-N-(2-NITROPHENYL)BENZENAMINE(1033225-43-2)
• EPA Substance Registry System: 2,6-DIFLUORO-N-(2-NITROPHENYL)BENZENAMINE(1033225-43-2)

Safety Data

• Hazardous Substances Data: 1033225-43-2(Hazardous Substances Data)

Usage

General Description

2,6-DIFLUORO-N-(2-NITROPHENYL)BENZENAMINE is a chemical compound that belongs to the class of organic compounds known as difluorobenzenes. It is a nitroaniline derivative with two fluorine atoms attached to the benzene ring. 2,6-DIFLUORO-N-(2-NITROPHENYL)BENZENAMINE is commonly used in the manufacture of pharmaceuticals, agrochemicals, and dyes. It has also been studied for its potential use as an intermediate in organic synthesis and in the development of new materials. Additionally, the compound has been shown to possess some biological activity, particularly as an inhibitor of certain enzymes. However, further research is needed to fully understand its potential applications and properties.

Upstream product

• 5509-65-9 2,6-difluoroaniline 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 1033225-44-3 N-(2,6-difluorophenyl)benzene-1,2-diamine 
• 1233485-17-0 1-(tert-butyloxycarbonyl)-3-(2,6-difluorophenyl)-1,3-dihydrobenzothiadiazole-S-oxide 
• 1233485-16-9 tert-butyl 2-(2,6-difluorophenylamino)phenylcarbamate 
• 1233485-20-5 1-(2,6-difluorophenyl)-1,3-dihydro-3-[2-(1-piperazinyl)ethyl]benzothiadiazole-S,S-dioxide succinate 
• 1033221-94-1 1-(2,6-difluorophenyl)-1,3-dihydro-3-[2-(1-piperazinyl)ethyl]benzothiadiazole-S,S-dioxide 
• 1033226-24-2 tert-butyl 4-(2-(3-(2,6-difluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl)ethyl)piperazine-1-carboxylate 
• 1233485-18-1 1-(tert-butyloxycarbonyl)-3-(2,6-difluorophenyl)-1,3-dihydrobenzothiadiazole-S,S-dioxide 
• 1033225-45-4 1-(2,6-difluorophenyl)-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxide 

Relevant articles and documents

Development of a pilot-plant-scale synthesis of an alkylated dihydrobenzothiadiazole S, S-dioxide: Incorporation of a late-stage mitsunobu reaction

The process used to prepare a functionalized dihydrobenzothiadiazole S,S-dioxide on a pilot plant scale is described. Key changes to the original synthesis included: modifying SNAr reaction conditions between a substituted aniline and 2-fluoron

ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE

The present invention is directed to aryl sulfamide derivatives of formula (I): or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.