1033363-02-8

Basic information

• Product Name: ethyl (1R,2R,3S,4R)-1-acetyl-4-hydroxy-4-methyl-3-nitro-2-m-tolyl-cyclohexanecarboxylate
• Synonyms: ethyl (1R,2R,3S,4R)-1-acetyl-4-hydroxy-4-methyl-3-nitro-2-m-tolyl-cyclohexanecarboxylate
• CAS NO: 1033363-02-8
• Molecular Weight: 363.411
• Mol File: 1033363-02-8.mol

Chemical Properties

• CAS DataBase Reference: ethyl (1R,2R,3S,4R)-1-acetyl-4-hydroxy-4-methyl-3-nitro-2-m-tolyl-cyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (1R,2R,3S,4R)-1-acetyl-4-hydroxy-4-methyl-3-nitro-2-m-tolyl-cyclohexanecarboxylate(1033363-02-8)
• EPA Substance Registry System: ethyl (1R,2R,3S,4R)-1-acetyl-4-hydroxy-4-methyl-3-nitro-2-m-tolyl-cyclohexanecarboxylate(1033363-02-8)

Safety Data

• Hazardous Substances Data: 1033363-02-8(Hazardous Substances Data)

Upstream product

• 35490-05-2 2-acetyl-5-oxohexanoic acid ethyl ester 
• 22568-43-0 1-methyl-3-(2-nitrovinyl)benzene 

Relevant articles and documents

ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS

Disclosed are processes of forming a compound (33), (35) or (37)

Organocatalytic asymmetric tandem Michael-Henry reactions: A highly stereoselective synthesis of multifunctionalized cyclohexanes with two quaternary stereocenters

(Chemical Equation Presented) A novel organocatalytic asymmetric tandem Michael-Henry reaction catalyzed by 9-amino-9-deoxyepiquinine (VI) has been developed. The reaction was efficiently catalyzed by catalyst VI to give highly functionalized cyclohexanes with four stereogenic carbons including two quaternary stereocenters in excellent enantioselectivities (97 to >99% ee) and high diastereoselectivities (93:7-99:1 dr). Thus, the first organocatalytic asymmetric Henry reaction of common ketones as acceptors is shown.