1033425-27-2Relevant academic research and scientific papers
A simple and convenient synthesis of 4-methyl-3-nitro-2-trihalomethyl-2H-chromenes from N-unsubstituted imines of 2-hydroxyacetophenones and trichloro(trifluoro)ethylidene nitromethanes
Korotaev, Vladislav Yu.,Sosnovskikh, Vyacheslav Ya.,Kutyashev, Igor B.,Barkov, Alexey Yu.,Matochkina, Evgeniya G.,Kodess, Mikhail I.
, p. 5055 - 5060 (2008/09/21)
The reaction of N-unsubstituted imines of 2-hydroxyacetophenones with trichloro(trifluoro)ethylidene nitromethanes in the presence of DABCO proceeds via tandem oxa-Michael/aza-Henry additions (in dichloromethane) or aza-Michael addition (in benzene) to give 4-methyl-3-nitro-2-trichloro(trifluoro)methyl-2H-chromenes or 1,1,1-trichloro(trifluoro)-3-nitro-N-[1-(2-hydroxyaryl)ethylidene]propan-2-amines, respectively.
