103343-66-4 Usage
General Description
The chemical compound, (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE, is a benzodiazepine derivative with a molecular structure that includes a benzene ring and a seven-membered diazepine ring. It is a chiral compound, with the (R)-enantiomer being the active form. Benzodiazepines are known for their sedative, anxiolytic, and muscle relaxant properties, and are commonly used in the treatment of anxiety, insomnia, and seizure disorders. The specific pharmacological effects of this compound may vary depending on its stereochemistry and the presence of other substituents on the molecule. Further research is needed to fully understand the potential therapeutic uses and safety profile of (R)-3-AMINO-1-METHYL-5-PHENYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE.
Check Digit Verification of cas no
The CAS Registry Mumber 103343-66-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,3,4 and 3 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 103343-66:
(8*1)+(7*0)+(6*3)+(5*3)+(4*4)+(3*3)+(2*6)+(1*6)=84
84 % 10 = 4
So 103343-66-4 is a valid CAS Registry Number.
103343-66-4Relevant articles and documents
Crystallization-induced asymmetric transformation: Stereospecific synthesis of a potent peripheral CCK antagonist
Reider,Davis,Hughes,Grabowski
, p. 955 - 957 (1987)
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PRODRUGS OF 1,4-BENZODIAZEPINONE COMPOUNDS
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Paragraph 00147, (2014/04/04)
Disclosed are compounds of Formula (I) and salts thereof, wherein: a) R1 is H or CH3, and R2 is Ry; or b) R1 is Rx and R2 is H; wherein Rx and Ry are disclosed herein.
5-PHENYL-LH-BENZ0 [E] [1, 4] DIAZEPINE COMPOUNDS SUBSTITUTED WITH AN HYDROXAMIC ACID GROUP AS HISTONE DEACETYLASE INHIBITORS
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Page/Page column 24, (2009/07/25)
Novel hydroxamate histone deacetylase inhibitors of formula (I) wherein X is C=O or CH2 used as antineoplastic agent.