1033480-91-9Relevant academic research and scientific papers
Pd-catalysed intramolecular regioselective arylation of 2-pyrones, pyridones, coumarins and quinolones by C–H bond functionalization
Nolan, Marie-Therese,Bray, Joshua T.W.,Eccles, Kevin,Cheung, Man Sing,Lin, Zhenyang,Lawrence, Simon E.,Whitwood, Adrian C.,Fairlamb, Ian J.S.,McGlacken, Gerard P.
, p. 7120 - 7127 (2017/09/12)
The intramolecular arylation of 2-pyrones, 2-pyridones, coumarins and quinolones is reported using PdII precatalyst sources without added phosphine ligands. The excellent yields and convenient reagents enables the formation of various analogues
Copper(I)-catalyzed intramolecular O-arylation for the synthesis of 2,3,4,9-tetrahydro-1 H -xanthen-1-ones with low loads of CuCl
Sudheendran, Kavitha,Malakar, Chandi C.,Conrad, Juergen,Beifuss, Uwe
, p. 10194 - 10210 (2013/01/15)
As little as 0.5 mol % CuCl is sufficient to catalyze the intramolecular O-arylation of easily accessible 2-(2-bromobenzyl)cyclohexane-1,3-diones to provide the corresponding 2,3,4,9-tetrahydro-1H-xanthen-1-ones with yields ranging from 83% to 99%.
Cu(I)-Catalyzed domino reactions: Efficient and selective synthesis of 4h-chromenes and naphthalenes
Malakar, Chandi C.,Schmidt, Dietmar,Conrad, Juergen,Beifuss, Uwe
supporting information; experimental part, p. 1972 - 1975 (2011/06/19)
Depending on the ratio of the substrates and the reaction conditions, the Cu(I)-catalyzed domino reaction between bromobenzyl bromides and β-ketoesters exclusively yields either 4H-chromenes or naphthalenes.
Intramolecular cyclization reaction - Palladium(0)-catalyzed cyclization is more effective than tin hydride mediated reaction
Majumdar, Krishna C.,Debnath, Pradip,Taher, Abu,Pal, Amarta K.
, p. 325 - 332 (2008/09/20)
Intramolecular CH arylation of pyrone, pyridone, uracil, imidazole, and benzimidazole derivatives are carried out in the presence of a Pd catalyst to form potentially bioactive fused heterocyclic compounds, whereas the n-Bu 3SnH-mediated aryl radical cyclization of the precursors 3 afforded mainly halogen-reduced uncyclized products.
