1033480-95-3Relevant academic research and scientific papers
Pd-catalysed intramolecular regioselective arylation of 2-pyrones, pyridones, coumarins and quinolones by C–H bond functionalization
Nolan, Marie-Therese,Bray, Joshua T.W.,Eccles, Kevin,Cheung, Man Sing,Lin, Zhenyang,Lawrence, Simon E.,Whitwood, Adrian C.,Fairlamb, Ian J.S.,McGlacken, Gerard P.
, p. 7120 - 7127 (2014)
The intramolecular arylation of 2-pyrones, 2-pyridones, coumarins and quinolones is reported using PdII precatalyst sources without added phosphine ligands. The excellent yields and convenient reagents enables the formation of various analogues
Pd/pivalic acid mediated direct arylation of 2-pyrones and related heterocycles
Pardo, Leticia M.,Prendergast, Aisling M.,Nolan, Marie-T.,Muimhneachin, Eoin,McGlacken, Gerard P.
, p. 3540 - 3550 (2015/06/08)
Abstract Direct arylation represents a favourable alternative to traditional cross-coupling reactions and has found widespread use with simple aryls and robust heterocycles. Herein a direct arylation protocol has been optimised and applied to more delicat
Intramolecular cyclization reaction - Palladium(0)-catalyzed cyclization is more effective than tin hydride mediated reaction
Majumdar, Krishna C.,Debnath, Pradip,Taher, Abu,Pal, Amarta K.
, p. 325 - 332 (2008/09/20)
Intramolecular CH arylation of pyrone, pyridone, uracil, imidazole, and benzimidazole derivatives are carried out in the presence of a Pd catalyst to form potentially bioactive fused heterocyclic compounds, whereas the n-Bu 3SnH-mediated aryl radical cyclization of the precursors 3 afforded mainly halogen-reduced uncyclized products.
