1033548-25-2

Basic information

• Product Name: 2-phenyl-N-(prop-2-enyl)-2H-1,2,4-benzothiadiazin-3-amine 1,1-dioxide
• Synonyms: 2-phenyl-N-(prop-2-enyl)-2H-1,2,4-benzothiadiazin-3-amine 1,1-dioxide
• CAS NO: 1033548-25-2
• Molecular Weight: 313.38
• Mol File: 1033548-25-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-phenyl-N-(prop-2-enyl)-2H-1,2,4-benzothiadiazin-3-amine 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-N-(prop-2-enyl)-2H-1,2,4-benzothiadiazin-3-amine 1,1-dioxide(1033548-25-2)
• EPA Substance Registry System: 2-phenyl-N-(prop-2-enyl)-2H-1,2,4-benzothiadiazin-3-amine 1,1-dioxide(1033548-25-2)

Safety Data

• Hazardous Substances Data: 1033548-25-2(Hazardous Substances Data)

Upstream product

• 1033547-77-1 N-phenyl-2-[(triphenylphosphoranylidene)amino]benzenesulfonamide 
• 1476-23-9 allylisocyanate 

Downstream Products

• 1033548-88-7 1-iodomethyl-4-phenyl-2,4-dihydro-1H-imidazo[2,1-c][1,2,4]-benzothiadiazine 5,5-dioxide 
• 1033548-95-6 1-methyl-4-phenyl-2,4-dihydro-1H-imidazo[2,1-c][1,2,4]-benzothiadiazine 5,5-dioxide 

Relevant articles and documents

Synthesis of diazaheterocyclic ring-fused 1,2,4-benzothiadiazine 1,1-dioxides by a sequential aza-Wittig/NH-addition cyclization/nucleophilic ring-closure methodology with N-alkenyl-2-carbodiimidobenzenesulfonamides as key intermediates

Treatment of N-alkenyl-2-azidobenzenesulfonamides with triphenylphosphane and subsequent subjection of the resulting iminophosphoranes to aza-Wittig reactions with isocyanates generated functionalized carbodiimides, which spontaneously underwent cyclization to form 2-alkenyl-3-(R2- substituted amino)-2H-1,2,4-benzothiadiazine 1,1-dioxides by internal nucleophilic addition. Subsequent (tandem) cyclizations through iodoamination or hydroamination with HgII/NaBH4 produced a variety of diazaheterocyclic ring-fused benzothiadiazine dioxides. In one case a methanobridged benzothiatriazabicyclotridecanone was obtained. The scope and limitations of these cyclizations are reported. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.