1033586-48-9Relevant articles and documents
Stereo- and regioselective azide/alkyne cycloadditions in carbonic anhydrase II via tethering, monitored by crystallography and mass spectrometry
Wischeler, Johannes Schulze,Sun, Dong,Sandner, Nicola U.,Linne, Uwe,Heine, Andreas,Koert, Ulrich,Klebe, Gerhard
, p. 5842 - 5851 (2011)
The carbonic anhydrase II mutant His64Cys was prepared and applied to tethered alkyne/azide cycloaddition reactions. The azide component could be tethered to the enzyme surface through a disulfide bridge, while the alkyne component was reversibly coordina
ETHINYL-PYRAZOLE DERIVATIVE
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Paragraph 0182; 0183, (2013/05/22)
Provided is a novel compound represented by formula [I] or a pharmaceutically acceptable salt thereof having antagonistic activity against group II metabolism-type glutamic acid (m-Glu) receptors. The compound or pharmaceutically acceptable salt thereof i