1033588-29-2Relevant academic research and scientific papers
Total synthesis of cytotoxic macrolide amphidinolide B1 and the proposed structure of amphidinolide B2
Lu, Liang,Zhang, Wei,Carter, Rich G.
, p. 7253 - 7255 (2008/12/20)
The first enantioselective total syntheses of cytotoxic macrolide amphidinolide B1 and the proposed structure for amphidinolide B2 have been accomplished. Key features of the syntheses include a diastereoselective aldol condensation, a spontaneous Wadsworth-Emmons macrocyclization and a directed epoxidation/elimination sequence. Copyright
