1033596-04-1Relevant academic research and scientific papers
Simple and convenient synthesis of 4-unsubstituted-3-(3-oxoalkyl) isocoumarins
Butin, Alexander V.,Dmitriev, Artem S.,Uchuskin, Maxim G.,Abaev, Vladimir T.,Trushkov, Igor V.
, p. 1569 - 1578 (2008/09/20)
A simple transformation of 2-alkylfurans and 2-formylbenzoic acids into 4-unsubstituted 3-(3-oxoalkyl)isocoumarins is described. It is based on the synthesis of 2-(2-carboxybenzyl)furans followed by their acid-catalyzed recyclization to the target isocoum
Isoquinolone derivatives via a furan recyclization reaction
Dmitriev, Artem S.,Abaev, Vladimir T.,Bender, Wolfgang,Butin, Alexander V.
, p. 9437 - 9447 (2008/02/10)
A new approach to the synthesis of isoquinolone derivatives has been developed. It is based on the protolytic recyclization of amides of 2-carboxybenzylfurans. It was shown that the reaction proceeds via formation of allylic alcohols of isoquinolone serie
