1033705-77-9

Usage

Uses

Used in Pharmaceutical Synthesis:
(5-Ethynylpyridin-2-yl)methanol is utilized as a key building block for the creation of various pharmaceuticals and biologically active molecules. Its distinctive structure and reactivity allow for the preparation of a broad spectrum of functionalized pyridine derivatives, which are vital for drug discovery and development.
Used in Material and Catalyst Development:
Due to its intriguing chemical properties, (5-Ethynylpyridin-2-yl)methanol may also be employed in the development of innovative materials and catalysts. Its unique characteristics make it a promising candidate for enhancing existing materials or creating new ones with improved performance.

Upstream product

• 650606-63-6 5-[2-(trimethylsilyl)ethynyl]pyridine-2-carbaldehyde 
• 940911-03-5 5-ethynyl-2-pyridinecarboxaldehyde 
• 88139-91-7 (5-bromopyridin-2-yl)methanol 

Relevant academic research and scientific papers

ANTIBACTERIAL AND ANTIFUNGAL PLEUROMUTILIN CONJUGATES

Compounds of formula (1) comprising a pleuromutilin backbone with a triazole based side-group at C22 are provided. The compounds can be used for treatment of bacterial infections and fungal infections. Importantly, infections caused by multidrug-resistant

RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

Provided herein are a RET inhibitor, a pharmaceutical composition thereof and uses thereof. In particular, provided is a compound having Formula (I) or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof. Provided is a pharmaceutical composition comprising the compound, and uses of the compound and pharmaceutical composition thereof for the preparation of a medicament, in particular for treatment and prevention of RET-related diseases and conditions, including cancer, irritable bowel syndrome, and/or pain associated with irritable bowel syndrome.

NOVEL CONDENSED PYRAZOLE DERIVATIVE AND MEDICAL USES THEREOF

PROBLEM TO BE SOLVED: To provide a preventive or therapeutic agent for mood disorder, anxiety disorder, schizophrenia, dementia, drug dependence or the like related to subtypes of metabolism type glutamate receptor (mGlu) 2 and 3. SOLUTION: There are prov

NEW PYRIDAZINE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS

The present invention relates to compounds of general formula I wherein the groups and radicals B, W, X, Y, Z, R1, R2, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.