1033717-19-9 Usage
Uses
Used in Pharmaceutical Industry:
1-Piperazinecarboxylic acid, 2,4-diMethyl-, 1,1-diMethylethyl ester, (2R)is used as an intermediate in the synthesis of various drugs, particularly in the production of antihistamines and antipsychotic medications. Its unique structure and chirality make it a valuable building block for the development of new therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 1-Piperazinecarboxylic acid, 2,4-diMethyl-, 1,1-diMethylethyl ester, (2R)serves as a key building block for the creation of more complex molecules. Its reactivity and functional groups allow for various chemical transformations, enabling the synthesis of a wide range of organic compounds.
Used in Chemical Research:
1-Piperazinecarboxylic acid, 2,4-diMethyl-, 1,1-diMethylethyl ester, (2R)is also utilized in chemical research to study the properties and reactivity of chiral compounds. Its unique structure provides insights into the stereochemistry of reactions and the development of enantioselective synthetic methods.
Safety Considerations:
It is important to handle 1-Piperazinecarboxylic acid, 2,4-diMethyl-, 1,1-diMethylethyl ester, (2R)with care, as it can be hazardous if not properly managed. Appropriate safety measures, such as wearing protective equipment and following proper disposal procedures, should be taken to minimize potential risks associated with this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 1033717-19-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,3,7,1 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1033717-19:
(9*1)+(8*0)+(7*3)+(6*3)+(5*7)+(4*1)+(3*7)+(2*1)+(1*9)=119
119 % 10 = 9
So 1033717-19-9 is a valid CAS Registry Number.
1033717-19-9Relevant academic research and scientific papers
Robinson, Steven P.,Sheikh, Nadeem S.,Baxter, Carl A.,Coldham, Iain
, p. 3642 - 3644 (2010)
Deprotonation of N-Boc-N′-alkylpiperazines with sec-BuLi in Et 2O-TMEDA gave the 2-lithio derivatives which were resolved in the presence of a chiral ligand. The best ligands for the asymmetric substitution were diamino-alkoxides that promoted a dynamic thermodynamic resolution (DTR) of the organolithium at -30 °C. Electrophilic quench gave enantiomerically enriched 2-substituted piperazines. Of a selection of piperazines, the N′-t-butyl derivative gave the best results, with the product N-Boc-N′-t-butyl-2-substituted piperazines being formed with enantiomer ratios up to 81:19.
