103372-31-2

Upstream product

• 13139-16-7 N-(tert-butyloxycarbonyl)-L-isoleucine 
• 106162-46-3 Boc-His(Tos)-LVA-Ile-Amp 
• 103882-43-5 (2S,4S,5S)-5-Amino-4-hydroxy-2-isopropyl-7-methyl-octanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide; hydrochloride 
• 103322-68-5 N-α-(tert-butyloxycarbonyl)-L-isoleucyl>-2-pyridylmethylamine 
• 97920-16-6 N-L-isoleucyl-2-pyridylmethylamine 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 103372-32-3 N-α-<4(S)-<(tert-butyldimethylsilyl)oxy>-5(S)-<(tert-butyloxycarbonyl)amino>-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine 
• 103406-77-5 (2S,4S,5S)-5-Amino-4-(tert-butyl-dimethyl-silanyloxy)-2-isopropyl-7-methyl-octanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 103372-33-4 {(S)-1-((1S,2S,4S)-2-(tert-Butyl-dimethyl-silanyloxy)-1-isobutyl-5-methyl-4-{(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butylcarbamoyl}-hexylcarbamoyl)-2-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-ethyl}-carbamic acid tert-butyl ester 
• 106162-46-3 N-im-tosyl-L-histidyl>-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine 

Downstream Products

• 112374-73-9 C₄₉H₇₄N₈O₈ 
• 112374-74-0 C₄₉H₇₃N₉O₈ 
• 103352-61-0 C₅₈H₈₃N₉O₉ 
• 112374-81-9 C₆₅H₈₉N₉O₁₁S 
• 134209-72-6 dansyl-Phe-His-LVA-Ile-Amp 
• 103352-48-3 (2S,4S,5S)-4-Hydroxy-5-[(S)-3-(1H-imidazol-4-yl)-2-(2-phenoxy-acetylamino)-propionylamino]-2-isopropyl-7-methyl-octanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 126082-57-3 (phenylacetyl)-L-histidyl-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-(methyloctanoyl)-L-isoleucyl-2-pyridylmethylamine 
• 103336-11-4 C₅₆H₈₀N₈O₁₀S 
• 112374-83-1 C₅₆H₇₉N₉O₁₀S 
• 126082-58-4 (phenylacetyl)-N^im-tosyl-L-histidyl-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-(methyloctanoyl)-L-isoleucyl-2-pyridylmethylamine 

Relevant academic research and scientific papers

Determination of Dissociation Constants of High Affinity (pM) Human Renin Inhibitors: Application to Analogues of Ditekiren (U-71,038)

A fluorescent human renin inhibitor, dansyl-Phe-His-LVA-Ile-Amp (3, U-80,825), was synthesized and utilized in a fluorescence energy transfer displacement assay to determine the dissociation constants (kd's) of a series of ditekiren analogues.T

Renin Inhibitory Peptides. A β-Aspartyl Residue as a Replacement for the Histidyl Residue at the P-2 Site

In an effort to decrease the size and to increase the hydrophilicity of the previously prepared renin inhibitory peptides, it was postulated that one might be able to take advantage of the polar Thr-84 on the flap region of the enzyme renin by potential h

Renin inhibitors containing ψ[CH2O]pseudopeptide inserts

Renin inhibitors 2-4 with the D-Lys renin inhibitory peptide (RIP) sequence, but containing Leuψ[CH2O]Ala (2), Leuψ[CH2O]Val (3), and Leuψ[CH2O]Leu (4) at the P1-P1' site, were of a comparable potency