1033735-90-8

Basic information

• Product Name: 5-(7-methyl-6-(3-(methylsulfonyl)phenyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine
• Synonyms: 5-(7-methyl-6-(3-(methylsulfonyl)phenyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine
• CAS NO: 1033735-90-8
• Molecular Weight: 481.599
• Mol File: 1033735-90-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(7-methyl-6-(3-(methylsulfonyl)phenyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(7-methyl-6-(3-(methylsulfonyl)phenyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine(1033735-90-8)
• EPA Substance Registry System: 5-(7-methyl-6-(3-(methylsulfonyl)phenyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine(1033735-90-8)

Safety Data

• Hazardous Substances Data: 1033735-90-8(Hazardous Substances Data)

Upstream product

• 827614-64-2 2-aminopyridine-5-boronic acid pinacol ester 
• 956393-39-8 4-(2-chloro-7-methyl-6-(3-(methylsulfonyl)phenyl)thieno[3,2-d]pyrimidin-4-yl)morpholine 

Relevant articles and documents

PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND METHODS OF USE

Compounds of Formulas Ia-d where X is S or O, mor is a morpholine group, and R3 is a monocyclic heteroaryl group, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for modulating the activity of lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia-d for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. Formula (Ic) and (Id).