1033748-17-2Relevant academic research and scientific papers
Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II with reduced p K a: Antibacterial agents with an improved safety profile
Reck, Folkert,Alm, Richard A.,Brassil, Patrick,Newman, Joseph V.,Ciaccio, Paul,McNulty, John,Barthlow, Herbert,Goteti, Kosalaram,Breen, John,Comita-Prevoir, Janelle,Cronin, Mark,Ehmann, David E.,Geng, Bolin,Godfrey, Andrew Aydon,Fisher, Stewart L.
, p. 6916 - 6933 (2012/10/07)
Novel non-fluoroquinolone inhibitors of bacterial type II topoisomerases (DNA gyrase and topoisomerase IV) are of interest for the development of new antibacterial agents that are not impacted by target-mediated cross-resistance with fluoroquinolones. N-L
2-QUINOLINONE AND 2-QUINOXALINONE- DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS
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Page/Page column 99, (2008/12/06)
The present invention relates to compounds of Formula (I) : and pharmaceutically acceptable salts thereof, to their use in the treatment of bacterial infections, and to their methods of preparation.
