1033777-14-8

Basic information

• Product Name: 4-adamantan-1-yl-N-[2-(4-benzyloxyphenyl)ethyl]-2-hydroxybutyramide
• CAS NO: 1033777-14-8
• Molecular Weight: 447.618
• Mol File: 1033777-14-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-adamantan-1-yl-N-[2-(4-benzyloxyphenyl)ethyl]-2-hydroxybutyramide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-adamantan-1-yl-N-[2-(4-benzyloxyphenyl)ethyl]-2-hydroxybutyramide(1033777-14-8)
• EPA Substance Registry System: 4-adamantan-1-yl-N-[2-(4-benzyloxyphenyl)ethyl]-2-hydroxybutyramide(1033777-14-8)

Safety Data

• Hazardous Substances Data: 1033777-14-8(Hazardous Substances Data)

Upstream product

• 1033777-81-9 C₁₄H₂₂O₃ 
• 51179-05-6 2-(4-(benzyloxy)phenyl)ethanamine 

Downstream Products

• 1033777-20-6 N-(4-(benzyloxy)phenethyl)-4-adamantyl-2-oxobutanamide 

Relevant articles and documents

Non-urea functionality as the primary pharmacophore in soluble epoxide hydrolase inhibitors

Inhibition of soluble epoxide hydrolase has been proposed as a promising new pharmaceutical target for diseases involving hypertension and vascular inflammation. The most potent sEH inhibitors reported to date contain a urea or amide moiety as the central or 'primary' pharmacophore. We evaluated replacing the urea pharmacophore with other functional groups such as thiourea, sulfonamide, sulfonylurea, aminomethylene amide, hydroxyamide, and ketoamide to identify novel and potent inhibitors. The hydroxyamide moiety was identified as a novel pharmacophore affording potency comparable to urea.