103391-83-9

Basic information

• Product Name: N-(2-(2-chlorophenyl)propyl)aniline
• Synonyms: N-(2-(2-chlorophenyl)propyl)aniline
• CAS NO: 103391-83-9
• Molecular Weight: 245.752
• Mol File: 103391-83-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-(2-chlorophenyl)propyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(2-chlorophenyl)propyl)aniline(103391-83-9)
• EPA Substance Registry System: N-(2-(2-chlorophenyl)propyl)aniline(103391-83-9)

Safety Data

• Hazardous Substances Data: 103391-83-9(Hazardous Substances Data)

Upstream product

• 6282-87-7 3-(2-chlorophenyl)-propanol 
• 89-98-5 2-chloro-benzaldehyde 
• 2039-87-4 2-chlorostyrene 
• 100-61-8 N-methylaniline 
• 62-53-3 aniline 
• 52085-97-9 3-(2-chlorophenyl)propionyl chloride 
• 111383-26-7 3-(2-chlorophenyl)-propionanilide 
• 30573-88-7 ethyl 3-(2-chlorophenyl)propanoate 

Downstream Products

• 3297-76-5 1-phenyl-1,2,3,4-tetrahydroquinoline 

Relevant articles and documents

Two-Step Procedure for the Synthesis of 1,2,3,4-Tetrahydro-quinolines

A new two-step procedure that includes an initial regioselective intermolecular hydroaminoalkylation of ortho-chlorostyrenes with N-methylanilines and a subsequent intramolecular Buchwald–Hartwig amination gives direct access to 1,2,3,4-tetrahydroquinolines. The hydroaminoalkylation reaction of the ortho-chlorostyrenes is catalyzed by a 2,6-bis(phenylamino)pyridinato titanium complex which delivers the linear regioisomers with high selectivities. In addition, the formation of unexpected dihydroaminoalkylation products from styrenes and N-methylanilines is reported.