1033931-99-5Relevant articles and documents
A domino annulation reaction under Willgerodt-Kindler conditions
Kadzimirsz, Daniel,Kramer, Daniel,Sripanom, Lertnarong,Oppel, Iris M.,Rodziewicz, Pawel,Doltsinis, Nikos L.,Dyker, Gerald
, p. 4644 - 4649 (2008)
(Chemical Equation Presented) Butanone side chains at arenes and hetarenes, efficiently introduced by a Heck-type reaction, are transformed to annulated thieno[3,2-b]thiophenes in a domino redox process under Willgerodt-Kindler conditions. A nucleophilic aromatic substitution with an intermediary thioenolate is a reasonable key step of this process.