103394-76-9

Basic information

• Product Name: 2-AMINO-3-PYRIDIN-2-YL-PROPIONIC ACID ETHYL ESTER
• Synonyms: 2-AMINO-3-PYRIDIN-2-YL-PROPIONIC ACID ETHYL ESTER;2-Pyridinepropanoic acid, .alpha.-amino-, ethyl ester;Ethyl 2-aMino-3-(2-pyridinyl)propionate;ethyl 2-aMino-3-(pyridin-2-yl)propanoate;(S)-2-AMINO-3-PIPERAZIN-1-YL-PROPIONIC ACID HCL
• CAS NO: 103394-76-9
• Molecular Formula: C10H14N2O2
• Molecular Weight: 194.23
• Mol File: 103394-76-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 290.2 °C at 760 mmHg
• Flash Point: 129.3 °C
• Appearance: /
• Density: 1.125 g/cm³
• Vapor Pressure: 0.0021mmHg at 25°C
• Refractive Index: 1.527
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-AMINO-3-PYRIDIN-2-YL-PROPIONIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-3-PYRIDIN-2-YL-PROPIONIC ACID ETHYL ESTER(103394-76-9)
• EPA Substance Registry System: 2-AMINO-3-PYRIDIN-2-YL-PROPIONIC ACID ETHYL ESTER(103394-76-9)

Safety Data

• Hazardous Substances Data: 103394-76-9(Hazardous Substances Data)

Usage

General Description

2-AMINO-3-PYRIDIN-2-YL-PROPIONIC ACID ETHYL ESTER is a chemical compound that consists of an amino group attached to a pyridine ring and a propionic acid ethyl ester. It is commonly used in pharmaceutical research and drug development due to its potential applications in the synthesis of various biologically active compounds. 2-AMINO-3-PYRIDIN-2-YL-PROPIONIC ACID ETHYL ESTER may possess different pharmacological properties, including anti-inflammatory, analgesic, and anti-cancer activities, making it a valuable building block for the synthesis of new drugs. Additionally, it is also used as a reagent in organic chemistry reactions, particularly in the formation of peptide and amide bonds. Overall, 2-AMINO-3-PYRIDIN-2-YL-PROPIONIC ACID ETHYL ESTER has important implications in both the pharmaceutical and chemical industries.

InChI:InChI=1/C10H14N2O2/c1-2-14-10(13)9(11)7-8-5-3-4-6-12-8/h3-6,9H,2,7,11H2,1H3

Upstream product

• 3243-01-4 ethyl 2-ethoxycarbonyl-3-(pyrid-2-yl)propionate 

Relevant articles and documents

OX2R COMPOUNDS

Methods and compositions for agonizing a type-2 orexin receptor (OX2R) in a cell determined to be in need thereof, including the general method of (a) administering to a subject a cyclic guanidinyl OX2R agonist and (b) detecting a resultant enhanced wakefulness or increased resistance to diet-induced accumulation of body fat, or abbreviated recovery from general anesthesia or jet lag.

Unnatural α-amino ethyl esters from diethyl malonate or ethyl β-bromo-α-hydroxyiminocarboxylate

We have explored here the scope of the age-old diethyl malonate-based accesses to α-amino esters involving Knoevenagel condensations of diethyl malonate on aldehydes, reductions of the resulting alkylidenemalonates, the preparation of the corresponding α-hydroxyimino esters and their final reduction. This synthetic pathway turned out to be general although some unexpected limitations were encountered. The synthetic modifications of some of the intermediates - using Suzuki-Miyaura coupling or cycloadditions - before undertaking the oximation step - provided accesses to further α-amino esters. Moreover, other pathways to α-hydroxyimino esters were explored including an attempt to improve the cycloadditions between ethyl β-bromo-α-hydroxyiminocarboxylate and various alkylfuranes.