1034019-13-0Relevant academic research and scientific papers
Synthesis and biological characterization of amidopropenyl hydroxamates as HDAC inhibitors
Thaler, Florian,Varasi, Mario,Colombo, Andrea,Boggio, Roberto,Munari, Davide,Regalia, Nickolas,Rozio, Marco G.,Reali, Veronica,Resconi, Anna E.,Mai, Antonello,Gagliardi, Stefania,Dondio, Giulio,Minucci, Saverio,Mercurio, Ciro
, p. 1359 - 1372 (2010)
A series of amidopropenyl hydroxamic acid derivatives were prepared as novel inhibitors of human histone deacetylases (HDACs). Several compounds showed potency at 50 values in tests again
Heterocyclic derivatives as HDAC inhibitors
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Page/Page column 16, (2009/12/27)
This invention is related to new histone deacetylase inhibitors according to the general formula (I) wherein: the dotted line is an optional additional bond; R1 is hydrogen, halogen, C1-C6 alkyl, C1-C6/sub
POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS
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Page/Page column 41-42, (2008/12/06)
The present invention relates to a novel compound or a salt thereof, which is useful as a CRTH2 antagonist, especially as a medicament for disorder that participates eosinophil, for example, allergic disorder such as asthma, allergic rhinitis, allergic dermatitis, conjunctival inflammation, hives, eosinophilic bronchitis, food allergy, inflammation of the nasal sinuses, multiple sclerosis, angiitis, or chronic obstructive pulmonary disease (COPD) and the like.
