1034028-72-2Relevant academic research and scientific papers
Structure-activity relationships of norepinephrine reuptake inhibitors with benzothiadiazine dioxide or dihydrosulfostyril cores
Fensome, Andrew,Goldberg, Joel,McComas, Casey C.,Trybulski, Eugene J.,Woodworth, Richard P.,Deecher, Darlene C.,Whiteside, Garth T.,Zhang, Puwen
scheme or table, p. 1555 - 1558 (2010/06/16)
Two related series of selective norepinephrine reuptake inhibitors were synthesized based on 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxide or 3,4-dihydrosulfostyril cores, and screened for monoamine reuptake inhibition. Structure-activity relationship
SUBSTITUTED BENZOTHIADIAZINEDIOXIDE DERIVATIVES AND METHODS OF THEIR USE
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Page/Page column 71, (2008/12/06)
The present invention is directed to substituted benzothiadiazinedioxide derivatives of formula (I) :or a pharmaceutically acceptable salt, stereoisomer or tautomer thereof, which are monoamine reuptake inhibitors, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions, including, inter alia, vasomotor symptoms, sexual dysfunction, gastrointestinal disorders and genitourinary disorder, depression disorders, endogenous behavioral disorders, cognitive disorders, diabetic neuropathy, pain, and other diseases or disorders.
