1034144-31-4

Basic information

• Product Name: 2-(2-fluoro-2-(phenylsulfonyl)vinyl)naphthalene
• CAS NO: 1034144-31-4
• Molecular Weight: 312.364
• Mol File: 1034144-31-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-fluoro-2-(phenylsulfonyl)vinyl)naphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-fluoro-2-(phenylsulfonyl)vinyl)naphthalene(1034144-31-4)
• EPA Substance Registry System: 2-(2-fluoro-2-(phenylsulfonyl)vinyl)naphthalene(1034144-31-4)

Safety Data

• Hazardous Substances Data: 1034144-31-4(Hazardous Substances Data)

Upstream product

• 1236300-73-4 1-tert-butyl-5-(fluoro(phenylsulfonyl)methylsulfonyl)-1H-tetrazole 
• 66-99-9 β-naphthaldehyde 
• 1034144-29-0 (1,3-benzothiazol-2-ylsulfonyl)fluoromethyl phenyl sulfone 

Relevant articles and documents

1-tert-Butyl-1H-tetrazol-5-yl fluoromethyl sulfone (TBTSO2CH2F): A versatile fluoromethylidene synthon and its use in the synthesis of monofluorinated alkenes via JuliaKocienski olefination

1-tert-Butyl-IH-tetrazol-5-yl fluoromethyl sulfone (TBTSO 2CI-12F) has been developed as a new and efficient fluoromethylidene synthon for the synthesis of both terminal and internal monofluoroalkenes via JuliaKocienski olefination reaction. The base-mediated reaction between TBTSO2CI-12F and carbonyl compounds (aldehydes and ketones) provided terminal monofluoroalkenes in good yields with moderate E!Z selectivity. The dominance of E- or Z-fluoroalkenes could be controlled by selection of proper reaction solvent and temperature. TBTSO 2CI-12F reagent was also found to be readily CL-alkylated, acylated, and phenylsulfonylated to give corresponding CL-functionalized fluorosulfones, which could be used in the synthesis of alkyl-, acyl-, and phenylsulfonyl-substituted internal monofluoroalkenes via JuliaKocienski olefination reactions.